Tentative Answer - Freud's Third Wound

3. Freud called his theory of the unconscious a ‘third wound’ to man’s self-esteem (pride). the first two were administered by Copernicus and Darwin. What might he have meant?

Looking back at history, the wound that Copernicus administered to man's self-esteem was his development of a heliocentric model of the solar system that contrasted to the geocentric model of the solar system that was in common use. This generally conflicted with what was accepted at the time in addition to conflicting with scripture. The idea that the Earth was not the center of the solar system affected man's idea that he was the counterpoint of the universe, which undermined man's superiority and status (thus affecting his self-esteem). 

Darwin's wound to man's self-esteem was his development of an evolutionary model that connects humans to other species, arguing that humans were evolved from lesser animals rather than created by a god. This also impacted man's relationship with scripture and divinity. As such, both of these first two wounds affected man's self-esteem by removing him from the 'center of the universe' and from the 'center of the earth' in terms of how significant man was in each sphere. 

Freud's theory of the unconscious was a third wound in this regard because it questioned man's free will and freedom over his own mind and actions. The idea that there was an unconscious that dictated some amount of action affected man's self-esteem in that it prevented man from being in complete control and having complete free will.